GS Paper III · Science & Tech
Diseases & Vaccines Current Affairs for UPSC (GS Paper III)
From the syllabus: Science and technology: developments and their applications and effects in everyday life; achievements of Indians; indigenization of technology; awareness in IT, space, computers, robotics, nano-technology, bio-technology; intellectual property rights
Why it matters: Examiners test epidemiological preparedness, indigenous vaccine development capacity, and global health cooperation mechanisms required to manage recurrent infectious disease outbreaks effectively.
In the news
October 2026
11 Oct 2026
Optogenetics Advances Offer Novel Frontiers in Biomedical ResearchRecent scientific reviews highlighting breakthroughs in optogenetics emphasize how light-based cellular manipulation has revolutionized neuroscience and parasitology. Researchers utilize light-sensitive proteins to control cellular...
11 Oct 2026
Public Health Vigilance Stepped up Following Shigella Outbreak in KeralaHealth authorities in Kerala sounded an alert following the detection of multiple Shigella infections in Thrissur district. Shigellosis is an intestinal infection caused by the Shigella bacterium, typically spread through contaminated...
11 Oct 2026
Experts Urge Active Surveillance to Disrupt Leprosy TransmissionPublic health specialists have called for aggressive household contact screening and early clinical intervention to halt the transmission cycle of leprosy across endemic pockets in India. Despite statistical national elimination...
10 Oct 2026
Need for Diverse Stem-Cell Donor Registries in IndiaMedical experts have emphasized the urgent need to expand and diversify India's stem-cell donor registries to treat blood cancers and genetic disorders like thalassemia. Because human leukocyte antigen (HLA) characteristics vary widely...
10 Oct 2026
Public Health Focus Shifts to Eliminating Leprosy TransmissionHealth experts have called for an updated public health strategy focused on cutting off community transmission of leprosy, rather than simply measuring statistical elimination based on prevalence rates. Despite India achieving the...
09 Oct 2026
Union Health Ministry Launches JOSH Teams for TB EliminationThe Union Health Minister has launched Joint Outreach and Support for Health (JOSH) teams to expedite India's goal of completely eliminating Tuberculosis. The program focuses on localized, community-led intervention to detect and...
08 Oct 2026
India's Strategic Role in the Global Pandemic AgreementAs negotiations continue under the World Health Organization, India's strategic leadership is critical to bridging differences between developed and developing nations in the draft Global Pandemic Agreement. The key debates focus on...
06 Oct 2026
Global Analysis Highlights Cancer Risks Associated with Epstein-Barr VirusA new comprehensive global analysis has highlighted the strong biological links between the common Epstein-Barr virus (EBV) and certain types of cancers, such as lymphomas and nasopharyngeal carcinoma. While the virus is highly...
05 Oct 2026
Siberian Pneumonic Plague Case Triggers Global Health AlertsA woman has died of pneumonic plague in Siberia, prompting localized health containment measures. Pneumonic plague is a highly infectious and severe form of plague that targets the lungs and can be fatal if not treated rapidly with...
05 Oct 2026
Discrepancies in National Rabies Mortality Data Highlight Surveillance GapsSignificant divergences have emerged across official death counts for rabies in India, with the Health Ministry's surveillance recording 50 deaths in 2023, the Registrar General of India recording 271, and an ICMR study estimating over...
04 Oct 2026
Helicobacter Pylori Eradication Essential to Reduce Gastric Cancer RiskNobel laureate Barry Marshall highlighted that chronic Helicobacter pylori infection causes long term stomach inflammation, significantly elevating gastric cancer risk. Early detection and complete eradication of the bacterium through...
04 Oct 2026
Early detection gaps pose hurdles to 2027 leprosy elimination goalHealth data reveals that over 3,800 children were diagnosed with leprosy in the latest reporting cycle, with dozens presenting Grade-2 visible disabilities at diagnosis. The presence of pediatric cases and delayed diagnoses presents a...
03 Oct 2026
Leprosy Transmission Interruption Targets Challenged by Rising Child CasesAs India strives to interrupt the transmission of leprosy by the year 2027, recent health data reveals that 3,832 children were diagnosed with the disease, with 37 of them already showing severe Grade 2 disabilities at the time of...
03 Oct 2026
CSIR-CCMB develops tool to predict Sickle Cell severityThe CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB) has developed an India-specific clinical severity scoring system for Sickle Cell Anemia (SCA). Existing international scoring systems often fail to accurately capture the...
02 Oct 2026
Ebola Death Toll Surpasses 4,000 in Democratic Republic of CongoThe World Health Organization (WHO) has raised a high-level alert over the rapid geographical spread of the Ebola virus into new health zones within the Democratic Republic of Congo. The death toll from the current outbreak has crossed...
September 2026
28 Sep 2026
Lancet Study Shows Waning Efficacy of TB Preventive Treatment in High-Burden SettingsA global study published in The Lancet indicated that the protective effect of Tuberculosis Preventive Treatment (TPT) may wane after one year in countries with high transmission rates. Researchers emphasized that pharmaceutical...
28 Sep 2026
Kerala Institute Develops Early Warning Model to Forecast Dengue OutbreaksScientists at the Institute of Advanced Virology (IAV) in Kerala have created a predictive early warning system to forecast dengue fever transmission trends. The predictive model incorporates meteorological variables, vector breeding...
17 Sep 2026
Rattlesnake blood proteins offer potential breakthrough in snakebite antivenomScientists have demonstrated that specific combinations of FETUA proteins extracted from western diamondback rattlesnakes can completely neutralise lethal rattlesnake venom in animal trials. The study showed that these natural blood...
17 Sep 2026
Revised Medical Protocols Urged for Melanoma Detection in IndiaMedical experts have called for updated screening protocols for melanoma in India, where the skin cancer presents differently than in Western populations. In India, melanoma commonly develops on the soles of feet and beneath nails,...
13 Sep 2026
Clinical Variations in Melanoma Presentation Flagged by Indian OncologistsHealth experts have highlighted that unlike Western populations where melanoma is primarily caused by UV-induced skin lesions, melanoma cases in India predominantly manifest as acral lentiginous melanoma on the soles of feet and beneath...
11 Sep 2026
Human Activity Influences Genetic Diversity of Dengue Mosquitoes in IndiaA scientific study highlights that human activities, rapid urbanization, and inter-city transport have significantly influenced the genetic structure and diversity of Aedes mosquitoes across India. Understanding vector movement and...
August 2026
31 Aug 2026
Ferritin Biomarkers Key to Detecting Hidden Iron DeficiencyMedical specialists highlight that individuals can suffer from severe iron deficiency even when blood haemoglobin levels appear normal. Depleted serum ferritin, which functions as the primary iron storage protein in human cells, acts as...
30 Aug 2026
Health alert issued following Swine Flu cases in statesState health departments have issued advisories following fresh cases of Swine Flu (H1N1 influenza), instructing hospitals to set up dedicated isolation wards and surveillance mechanisms. H1N1 is a contagious respiratory virus that...
29 Aug 2026
Clinical Trials Highlight Breakthrough Potential of mRNA Tumour VaccinesRecent clinical trials on mRNA-based tumour vaccines for melanoma have demonstrated promising therapeutic potential, marking a major advancement in personalized cancer treatment. Unlike traditional vaccines that prevent infectious...
28 Aug 2026
Democratic Republic of Congo initiates mass Ebola vaccination campaignThe Democratic Republic of Congo launched its largest Ebola vaccination campaign following its worst outbreak on record, which expanded across 60 health zones. Health authorities received over 50,000 doses of Ervebo, a single-dose...
Show 32 older stories
August 2026
25 Aug 2026
ICMR reports H1N1 strain accounts for majority of Influenza A casesThe Indian Council of Medical Research (ICMR) reported that the H1N1 subtype accounts for nearly 98% of all Influenza A cases tested across the country. ICMR leadership advised that there is no need for widespread panic or mandatory...
25 Aug 2026
Centre Restricts Fixed-Dose Cold Medicines for Children Under FourThe Union Ministry of Health and Family Welfare restricted the use of fixed-dose combination (FDC) medicines containing chlorpheniramine maleate and phenylephrine for children below four years of age. The move follows international...
24 Aug 2026
ICMR Reassures Public on Circulating H1N1 Strains and Vaccine EfficacyThe Indian Council of Medical Research (ICMR) confirmed that there are no new mutant strains of the H1N1 influenza virus circulating in the country. The health research body affirmed that current influenza strains match existing...
23 Aug 2026
Health Ministry Restricts Common Cold Combination Drugs for Young ChildrenThe Union Health Ministry has restricted the use of Fixed Dose Combination (FDC) drugs containing Chlorpheniramine Maleate and Phenylephrine Hydrochloride for children below four years of age. These ingredients, commonly found in...
22 Aug 2026
DRC Receives Ervebo Vaccine Doses to Contain Ebola OutbreakOver 16,000 doses of the Ervebo vaccine arrived in the Democratic Republic of the Congo to contain an ongoing Ebola outbreak. Ervebo is an injectable recombinant vaccine previously deployed during the major 2018-2020 West African and...
22 Aug 2026
Clinical Trial Shows mRNA Cancer Drug Efficacy Against MelanomaA large, late-stage clinical trial evaluating an investigational mRNA-based cancer drug showed significant efficacy in curbing the recurrence of melanoma. This marks the first time an mRNA therapeutic platform has demonstrated positive...
21 Aug 2026
Study Uncovers Inappropriate Tuberculosis PrescriptionsA systematic review analyzing 34 health studies revealed that over 53 percent of anti-tuberculosis prescriptions outside national healthcare programs failed to adhere to standard treatment guidelines. The study estimated that two to...
21 Aug 2026
Shigellosis Outbreak Prompts Public Health Advisories in KeralaCases of Shigellosis, a highly contagious bacterial intestinal infection, have resurfaced in Kerala, prompting state health officials to issue urgent public sanitation warnings. The infection spreads primarily through contaminated...
19 Aug 2026
Ebola Outbreak in Congo Surpasses 5,000 CasesThe ongoing Ebola virus disease outbreak in the Democratic Republic of the Congo has surpassed 5,000 cases, resulting in over 2,300 deaths. Health authorities report that violent conflict, population displacement, and dense mobility are...
19 Aug 2026
Surge in H1N1 Cases Prompts Public Health AlertSeveral states, including Delhi, have registered a sharp spike in seasonal H1N1 influenza cases compared to previous years. Public health specialists have advised against panic while recommending targeted measures, such as timely...
July 2026
29 Jul 2026
Study reveals complex dengue burden with co-circulating strainsA nationwide surveillance study by ICMR-VRDL has found that multiple virus strains of dengue are circulating simultaneously in India. This co-circulation increases the risk of severe disease and presents significant hurdles for the...
28 Jul 2026
Balancing Safety and Access in Dengue Vaccine DeploymentAs India considers the deployment of the Qdenga dengue vaccine, public health experts are urging the government to ensure its affordability. Given the high burden of dengue in tropical regions, making the vaccine accessible to...
28 Jul 2026
Rising Amoebic Meningitis Fatalities Concern Public Health OfficialsKerala has reported another death due to primary amebic meningoencephalitis, commonly known as amoebic brain fever. Public health officials are struggling to pinpoint the exact source of the infection, raising concerns about safety...
27 Jul 2026
Call for Affordable Rollout of Qdenga Dengue Vaccine in IndiaPublic health advocates have emphasized the need for an affordable, country-wide rollout of the Qdenga live-attenuated dengue vaccine in India. Dengue is a major vector-borne health threat in India, placing substantial economic and...
26 Jul 2026
Rajasthan battles Chandipura virus casesRajasthan has intensified health surveillance measures after two deceased young girls tested positive for the Chandipura virus. This emerging vector-borne pathogen primarily targets children under the age of 15, causing sudden high...
23 Jul 2026
US FDA Reviews the Unregulated Market of Therapeutic PeptidesThe US Food and Drug Administration (FDA) is cracking down on the compounding of several popular synthetic peptides, including BPC-157, TB-500, and Semax, due to a severe lack of human clinical trial data. These substances are widely...
23 Jul 2026
US Generic Drug Tariff Threats Loom Over Indian Pharma SectorFormer US President Donald Trump has proposed a 100 percent tariff on generic drugs after a two-year zero-tariff window, raising it further to 200 percent subsequently. Indian pharmaceutical exporters, who supply a significant portion...
23 Jul 2026
IISc Researchers Develop Novel Method for Oral Cancer TreatmentResearchers at the Indian Institute of Science (IISc) have developed a promising, non-invasive method to treat oral cancer cells using magnetic nanoparticles. By deploying these specialized nanoparticles, scientists can selectively...
22 Jul 2026
India Approves Its First Dengue Vaccine QDENGAQDENGA has received official approval for use in India, marking a major milestone in public health and disease prevention. The vaccine is designed to protect against all four serotypes of the dengue virus, which is endemic across the...
17 Jul 2026
Breakthrough daily pill targets high LDL cholesterolMedical researchers have developed a breakthrough daily oral pill that significantly reduces low-density lipoprotein (LDL) cholesterol, offering a powerful alternative to injectable treatments. Unlike traditional statins which can have...
17 Jul 2026
Concerns over Cyclospora parasite outbreakMedical experts have raised concerns over Cyclospora, a parasite that causes 'explosive diarrhea' and is increasingly being reported. The outbreak highlights the need for better food safety protocols and cross-border cooperation to...
15 Jul 2026
New Zealand Records First Ever Case of H5 Bird FluNew Zealand has detected its first-ever case of the highly pathogenic H5 bird flu in a brown skua, an ocean-going seabird found on Petone Beach in Wellington. This biosecurity alert has put wildlife authorities on high vigilance due to...
15 Jul 2026
Protein Biosensors Emerge as Game-Changers in Medical EmergenciesScientists are increasingly utilizing protein biosensors and aptamers as advanced recognition elements to detect disease-relevant proteins rapidly. Because proteins govern almost all biological processes, these biosensors can...
10 Jul 2026
Breakthrough weekly insulin shot for diabetes treatmentMedical experts are highlighting the potential of the world's first weekly insulin injection to transform diabetes care in India. Moving from daily to weekly shots is expected to improve patient compliance and reduce the long-term...
09 Jul 2026
Fatal Chandipura Virus Infection Reported in GujaratA child has died from a Chandipura virus infection in Gujarat's Sabarkantha district, triggering public health alerts in the region. Part of the Rhabdoviridae family, the Chandipura virus is transmitted primarily by sandflies and...
09 Jul 2026
Dengue Surge Forces Sri Lankan Universities to Move OnlineSri Lankan universities have closed and shifted to online classes as the island nation battles a massive surge in dengue cases. The National Dengue Control Unit reported over 65,000 cases, with the capital city of Colombo accounting for...
09 Jul 2026
Parrot Bornavirus 4 (PaBV-4) Identified for the First Time in IndiaResearchers have identified the parrot bornavirus 4 (PaBV-4) in captive birds in India for the first time. This virus, which can cause neurological issues in birds, poses a significant threat to aviculture and the conservation of...
06 Jul 2026
Scientists Call for Region-Specific Antivenom in IndiaExperts have highlighted that India's reliance on a single polyvalent antivenom is insufficient due to the heterogeneity in snake venom across different states. To improve survival rates, the country needs region-specific formulations...
05 Jul 2026
Clinical Trials for New Ebola Treatments Begin in DRCA clinical trial testing new therapeutic drugs for Ebola has commenced in the Democratic Republic of the Congo (DRC) city of Bunia. The region is currently tackling a resurgence of the virus, and the trial offers hope to local...
04 Jul 2026
WHO Places Bundibugyo Ebola Molecular Test under Emergency Use ListingThe World Health Organization (WHO) has granted its first Emergency Use Listing (EUL) for a molecular diagnostic test designed for the Bundibugyo ebolavirus. Concurrently, clinical trials have commenced in the Democratic Republic of...
03 Jul 2026
Rollout of Human Papillomavirus (HPV) Vaccination to Combat Cervical CancerPublic health departments across several Indian states are intensifying the rollout of the Human Papillomavirus (HPV) vaccine. This major public health initiative aims to dramatically reduce the incidence of cervical cancer, which...
03 Jul 2026
Digital Vaccines: The Interface of AI and Behavioral Public HealthResearchers are highlighting the emerging field of "digital vaccines", technological interventions where artificial intelligence and behavioral science are combined to influence human habits and prevent metabolic and non-communicable...
Practise Diseases & Vaccines
10 of our latest questions on this topic (out of 61).
Question 1 of 10
Shigellosis, an acute intestinal infection that causes frequent local health alerts, is characterized by which of the following microbiological features?
Previous years' questions
Past exam questions sorted by topic are coming here. Until then, the full papers are in our previous papers library.